Transdiagnostic failure to adapt interoceptive precision estimates across affective, substance use, and eating disorders: A replication study.

ABSTRACT: Recent computational theories of interoception suggest that perception of bodily states rests upon an expected reliability- or precision-weighted integration of afferent signals and prior beliefs. The computational psychiatry framework further suggests that aberrant precision-weighting may lead to misestimation of bodily states, potentially hindering effective visceral regulation and promoting psychopathology. In a previous study, we fit a Bayesian computational model of perception to behavior on a heartbeat tapping task to test whether aberrant precision-weighting was associated with misestimation of bodily states. We found that, during an interoceptive perturbation designed to amplify afferent signal precision (inspiratory breath-holding), healthy individuals increased the precision-weig

SUBMITTER: Lavalley CA 

PROVIDER: S-EPMC10593015 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature