Mildly elevated INR is associated with worse outcomes following mechanical thrombectomy for acute ischemic stroke.

ABSTRACT:

Background

Elevated International Normalized Ratio (INR) is a marker of coagulopathy, but its impact on outcomes following mechanical thrombectomy (MT) in patients with stroke is unclear. This study investigates the impact of mild INR elevations on clinical outcomes following MT.

Methods

In this retrospective cohort study, consecutive patients with stroke treated with MT were identified from 2015 to 2020 at a Comprehensive Stroke Center. Demographic information, past medical history, INR, National Institutes of Health Stroke Scale score, use of tissue plasminogen activator, and last known normal to arteriotomy time were recorded. Outcome measures included modified Thrombolysis in Cerebral Infarction (mTICI) score, modified Rankin Scale (mRS) score at 90 days, and intracerebr

SUBMITTER: Chen H 

PROVIDER: S-EPMC10593142 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature