The Placebo Effect in Psychosis: Why It Matters and How to Measure It.

ABSTRACT: Psychosis is characterized by unusual percepts and beliefs in the form of hallucinations and delusions. Antipsychotic medication, the primary treatment for psychosis, is often ineffective and accompanied by severe side effects, but research has not identified an effective alternative in several decades. One reason that clinical trials fail is that patients with psychosis tend to show a significant therapeutic response to inert control treatments, known as the placebo effect, which makes it difficult to distinguish drug effects from placebo effects. Conversely, in clinical practice, a strong placebo effect may be useful because it could enhance the overall treatment response. Identifying factors that predict large placebo effects could improve the future outlook of psychosis treatment. Biom

SUBMITTER: Hird EJ 

PROVIDER: S-EPMC10593894 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature