A Multilevel Examination of Cognitive Control in Adolescents With Nonsuicidal Self-injury.

ABSTRACT:

Background

Nonsuicidal self-injury (NSSI), a transdiagnostic behavior, often emerges during adolescence. This study used the Research Domain Criteria approach to examine cognitive control (CC) with a focus on response inhibition and urgency relative to NSSI severity in adolescents.

Methods

One hundred thirty-eight adolescents, assigned female sex at birth, with a continuum of NSSI severity completed negative and positive urgency measurements (self-report), an emotional Go/NoGo task within negative and positive contexts (behavioral), and structural and functional imaging during resting state and task (brain metrics). Cortical thickness, subcortical volume, resting-state functional connectivity, and task activation focused on an a priori-defined CC network. Eighty-four partici

SUBMITTER: Basgoze Z 

PROVIDER: S-EPMC10593942 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature