Chemotherapy-Related Toxic Effects and Quality of Life and Physical Functioning in Older Patients.

ABSTRACT:

Importance

Although older patients are at increased risk of developing grade 3 or higher chemotherapy-related toxic effects, no studies, to our knowledge, have focused on the association between toxic effects and quality of life (QOL) and physical functioning.

Objective

To investigate the association between grade 3 or higher chemotherapy-related toxic effects and QOL and physical functioning over time in older patients.

Design, setting, and participants

In this prospective, multicenter cohort study, patients aged 70 years or older who were scheduled to receive chemotherapy with curative or palliative intent and a geriatric assessment were included. Patients were treated with chemotherapy between December 2015 and December 2021. Quality of life and physical functionin

SUBMITTER: Baltussen JC 

PROVIDER: S-EPMC10594146 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature