Performance of ultra-sensitive malaria rapid diagnostic test to detect Plasmodium falciparum infection in pregnant women in Kinshasa, the Democratic Republic of the Congo.

ABSTRACT:

Background

Low peripheral parasitaemia caused by sequestration of Plasmodium falciparum in the placenta hampers the diagnosis of malaria in pregnant women, leading to microscopy or conventional rapid diagnostic tests (RDTs) false-negative results. Although mainly asymptomatic, maternal malaria remains harmful to pregnant women and their offspring in endemic settings and must be adequately diagnosed. Ultra-sensitive RDTs (uRDTs) are thought to be more sensitive than RDTs, and their diagnostic performance was assessed in the current study in pregnant women living in Kinshasa, a stable malaria transmission area in the Democratic Republic of the Congo.

Methods

To assess and compare the diagnostic performances of both RDTs and uRDTs, 497 peripheral blood samples were tested using

SUBMITTER: Kabalu Tshiongo J 

PROVIDER: S-EPMC10594769 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature