Respective Effects of Helmet Pressure Support, Continuous Positive Airway Pressure, and Nasal High-Flow in Hypoxemic Respiratory Failure: A Randomized Crossover Clinical Trial.

ABSTRACT: Rationale: The respective effects of positive end-expiratory pressure (PEEP) and pressure support delivered through the helmet interface in patients with hypoxemia need to be better understood. Objectives: To assess the respective effects of helmet pressure support (noninvasive ventilation [NIV]) and continuous positive airway pressure (CPAP) compared with high-flow nasal oxygen (HFNO) on effort to breathe, lung inflation, and gas exchange in patients with hypoxemia (Pa_O2/Fi_O2 ⩽ 200). Methods: Fifteen patients underwent 1-hour phases (constant Fi_O2) of HFNO (60 L/min), helmet NIV (PEEP = 14 cm H₂O, pressure support = 12 cm H₂O), and CPAP (PEEP = 14 cm H₂O) in randomized s

SUBMITTER: Menga LS 

PROVIDER: S-EPMC10595442 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature