Inhaled Fluticasone Furoate for Outpatient Treatment of Covid-19.

ABSTRACT:

Background

The effectiveness of inhaled glucocorticoids in shortening the time to symptom resolution or preventing hospitalization or death among outpatients with mild-to-moderate coronavirus disease 2019 (Covid-19) is unclear.

Methods

We conducted a decentralized, double-blind, randomized, placebo-controlled platform trial in the United States to assess the use of repurposed medications in outpatients with confirmed coronavirus disease 2019 (Covid-19). Nonhospitalized adults 30 years of age or older who had at least two symptoms of acute infection that had been present for no more than 7 days before enrollment were randomly assigned to receive inhaled fluticasone furoate at a dose of 200 μg once daily for 14 days or placebo. The primary outcome was the time to sustained rec

SUBMITTER: Boulware DR 

PROVIDER: S-EPMC10597427 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature