Positive Predictive Value for Multitarget Stool DNA After Bariatric and Metabolic Surgery.

ABSTRACT:

Background and aims

Bariatric and metabolic surgery (BMS) may adversely affect noninvasive stool tests for colorectal cancer (CRC) screening through several mechanisms. Multitarget stool DNA (mt-sDNA) is approved for CRC screening; however, performance in post-BMS patients is unknown. As the rates of BMS are anticipated to increase with rising incidence of obesity, it is important to evaluate mt-sDNA test performance among these patients.

Methods

In a multisite academic and community-based practice, we obtained mt-sDNA results from 10/2014 to 12/2019 through electronic records and an institutional BMS registry. Average CRC risk patients with BMS prior to a positive mt-sDNA underwent a detailed chart review. Follow-up colonoscopy findings were compared to those among BMS pati

SUBMITTER: Ebner DW 

PROVIDER: S-EPMC10597571 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature