Neurophysiological oscillatory markers of hypoalgesia in conditioned pain modulation.

ABSTRACT:

Introduction

Conditioned pain modulation (CPM) is an experimental procedure that consists of an ongoing noxious stimulus attenuating the pain perception caused by another noxious stimulus. A combination of the CPM paradigm with concurrent electrophysiological recordings can establish whether an association exists between experimentally modified pain perception and modulations of neural oscillations.

Objectives

We aimed to characterize how CPM modifies pain perception and underlying neural oscillations. We also interrogated whether these perceptual and/or neurophysiological effects are distinct in patients affected by chronic pain.

Methods

We presented noxious electrical stimuli to the right ankle before, during, and after CPM induced by an ice pack placed on the left

SUBMITTER: Jin H 

PROVIDER: S-EPMC10597579 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature