Body mass index-dependent immunological profile changes after left ventricular assist device implantation.

ABSTRACT:

Purpose

Infection is a common complication following left ventricular assist device (LVAD) implantation. Patients with obesity are particularly at risk due to their high percentage of adipose tissue and the resulting chronic inflammatory state and resulting immunological changes. This study investigated changes of immunological parameters in relation to body mass index (BMI) during the first year after LVAD implantation.

Methods

Blood samples were obtained prior to LVAD implantation and at 3 (1^st FU), 6 (2^nd FU) and 12 mo (3^rd FU) after LVAD implantation. Patients were divided into three groups (normal weight: BMI of 18.5-24.9 kg/m²; n=12; pre-obesity: 25.0-29.9 kg/m²; n=15; obesity: ≥ 30.0 kg/m²; n=17) based

SUBMITTER: Klaeske K 

PROVIDER: S-EPMC10597783 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature