Diffusion MRI of the facial-vestibulocochlear nerve complex: a prospective clinical validation study.

ABSTRACT:

Objectives

Surgical planning of vestibular schwannoma surgery would benefit greatly from a robust method of delineating the facial-vestibulocochlear nerve complex with respect to the tumour. This study aimed to optimise a multi-shell readout-segmented diffusion-weighted imaging (rs-DWI) protocol and develop a novel post-processing pipeline to delineate the facial-vestibulocochlear complex within the skull base region, evaluating its accuracy intraoperatively using neuronavigation and tracked electrophysiological recordings.

Methods

In a prospective study of five healthy volunteers and five patients who underwent vestibular schwannoma surgery, rs-DWI was performed and colour tissue maps (CTM) and probabilistic tractography of the cranial nerves were generated. In patients, th

SUBMITTER: Shapey J 

PROVIDER: S-EPMC10598116 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature