Obesity and its influence on liver dysfunction, morbidity and mortality after liver resection.

ABSTRACT:

Background

Obesity and associated steatosis is an increasing health problem worldwide. Its influence on post-hepatectomy liver failure (PHLF) and after liver resection (LR) is still unclear.

Methods

Patients who underwent LR were investigated and divided into three groups [normal weight: body mass index (BMI) 18.5-24.9 kg/m², overweight: BMI 25.0-29.9 kg/m², obese: BMI ≥30 kg/m²] in this retrospective study. Primary aim of this study was to assess the influence of BMI and nonalcoholic steatohepatitis (NASH) on PHLF and morbidity.

Results

Of 888 included patients, 361 (40.7%) had normal weight, 360 (40.5%) were overweight, 167 (18.8%) were obese. Median age was 62.5 years (IQR, 54-69 years). The primary indication for LR was colorectal

SUBMITTER: Kampf S 

PROVIDER: S-EPMC10598315 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature