BDNF gene Val66Met polymorphisms as a predictor for clinical presentation in schizophrenia - recent findings.

ABSTRACT: Schizophrenia is a highly heritable, severe psychiatric disorder that involves dysfunctions in thinking, emotions, and behavior, with a profound impact on a person's ability to function normally in their daily life. Research efforts continue to focus on elucidating possible genetic underlying mechanisms of the disorder. Although the genetic loci identified to date to be significantly associated with schizophrenia risk do not represent disease-causing factors, each one of them could be seen as a possible incremental contributor. Considering the importance of finding new and more efficient pharmacological approaches to target the complex symptomatology of this disorder, in this scoping review, we are focusing on the most recent findings in studies aiming to elucidate the contribution of one

SUBMITTER: Farcas A 

PROVIDER: S-EPMC10598753 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature