Antimullerian hormone and leukocyte aging markers in the Coronary Artery Risk Development in Young Adults study.

ABSTRACT:

Objective

To examine whether premenopausal reproductive age, as indicated by serum antimüllerian hormone (AMH), is associated with leukocyte aging biomarkers.

Design

Prospective cohort analysis.

Setting

The Coronary Artery Risk Development in Young Adults study, a population-based study of Black and White adults from four US communities (Birmingham, AL; Chicago, IL; Minneapolis, MN; Oakland, CA).

Patient(s)

Premenopausal women with serum AMH measures at examination year 15 as well as leukocyte aging markers.

Intervention(s)

None.

Main outcome measure(s)

Telomere length, mitochondrial deoxyribonucleic acid (mtDNA) copy number, and intrinsic and extrinsic epigenetic age acceleration (EAA) at examination years 15, 20, and 25 as well as change between

SUBMITTER: Kim C 

PROVIDER: S-EPMC10598775 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature