Circular and L50-like leaderless enterocins share a common ABC-transporter immunity gene.

ABSTRACT: Microbes live within complex communities of interacting populations, either free-living in waters and soils or symbionts of animals and plants. Their interactions include the production of antimicrobial peptides (bacteriocins) to antagonize competitors, and these producers must carry their own immunity gene for self-protection. Whether other coexisting populations are sensitive or resistant to the bacteriocin producer will be key for the population dynamics within the microbial community. The immunity gene frequently consists of an ABC transporter to repel its own bacteriocin but rarely protects against a nonrelated bacteriocin. A case where this cross-resistance occurs mediated by a shared ABC transporter has been shown between enterocins MR10A/B and AS-48. The first is an L50-like leader

SUBMITTER: Teso-Perez C 

PROVIDER: S-EPMC10598978 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature