Serum uric acid is associated with chronic kidney disease in elderly Chinese patients with diabetes.

ABSTRACT:

Background

The relationship between hyperuricemia and chronic kidney disease (CKD) has been investigated extensively. However, studies on elderly individuals are still limited. Moreover, there is no consensus on whether hyperuricemia or elevated serum uric acid (SUA) within the normal range is correlated with the new onset of CKD and whether there are differences between males and females.

Methods

We included 39039 elderly diabetic patients without CKD at baseline from a community-based cohort in Wuhan, China. The outcome event was the new onset of CKD (defined as an estimated glomerular filtration rate < 60 mL/min/1.73 m²). Multivariate Cox models were used to assess the adjusted hazard ratio (HR).

Results

During the 2-year follow-up period, 3162 (8.10%) p

SUBMITTER: Zhou Q 

PROVIDER: S-EPMC10599260 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature