Links between brain neuroimaging and blood inflammatory markers in urological chronic pelvic pain syndrome.

ABSTRACT: Urological chronic pelvic pain syndrome (UCPPS) is a debilitating painful condition with unclear etiology. Prior researchers have indicated that compared to healthy controls, patients with UCPPS demonstrated altered brain activity. Researchers have also shown that in UCPPS, several blood inflammatory markers relate to clinical variables of pain, fatigue, and pain widespreadness. However, how altered brain function in patients with UCPPS relates to blood inflammation remains unknown. To extend and connect prior findings of altered brain function and inflammatory factors in UCPPS, we conducted a secondary analysis of data from a cohort of UCPPS patients (N = 29) and healthy controls (N = 31) who provided both neuroimaging and blood data (National Institute of Health MAPP Research Network pub

SUBMITTER: Martucci KT 

PROVIDER: S-EPMC10599305 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature