ORFanID: A web-based search engine for the discovery and identification of orphan and taxonomically restricted genes.

ABSTRACT: With the numerous genomes sequenced today, it has been revealed that a noteworthy percentage of genes in a given taxon of organisms in the phylogenetic tree of life do not have orthologous sequences in other taxa. These sequences are commonly referred to as "orphans" or "ORFans" if found as single occurrences in a single species or as "taxonomically restricted genes" (TRGs) when found at higher taxonomic levels. Quantitative and collective studies of these genes are necessary for understanding their biological origins. However, the current software for identifying orphan genes is limited in its functionality, database search range, and very complex algorithmically. Thus, researchers studying orphan genes must harvest their data from many disparate sources. ORFanID is a graphical web-based

SUBMITTER: Gunasekera RS 

PROVIDER: S-EPMC10599687 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature