Association between diabetes at different diagnostic ages and risk of cancer incidence and mortality: a cohort study.

ABSTRACT:

Background

Different ages for diagnosis of diabetes have diverse effects on risks of cardiovascular disease, dementia, and mortality, but there is little evidence of cancer. This study investigated the relationship between diabetes at different diagnostic ages and risks of cancer incidence and mortality in people aged 37-73 years.

Methods

Participants with diabetes in the UK Biobank prospective cohort were divided into four groups: ≤40, 41-50, 51-60, and >60 years according to age at diagnosis. A total of 26,318 diabetics and 105,272 controls (1:4 randomly selected for each diabetic matched by the same baseline age) were included. We calculated the incidence density, standardized incidence, and mortality rates of cancer. Cox proportional hazard model was used to examine the

SUBMITTER: Peng Y 

PROVIDER: S-EPMC10600378 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature