Rationale, design, and cohort characteristics of the Action for Health in Diabetes Aging study.

ABSTRACT:

Introduction

Diabetes and overweight/obesity are described as accelerating aging processes, yet many individuals with these conditions maintain high levels of cognitive and physical function and independence late into life. The Look AHEAD Aging study is designed to identify 20-year trajectories of behaviors, risk factors, and medical history associated with resilience against geriatric syndromes and aging-related cognitive and physical functional deficits among individuals with these conditions.

Methods

Look AHEAD Aging extends follow-up of the cohort of the former 10-year Look AHEAD trial. The original cohort (N = 5145) was enrolled in 2001 to 2004 when participants were aged 45 to 76 years and randomly assigned to a multidomain intensive lifestyle intervention (ILI)

SUBMITTER: Espeland MA 

PROVIDER: S-EPMC10600408 | biostudies-literature | 2023 Oct-Dec

REPOSITORIES: biostudies-literature