Language lateralization mapping (reversibly) masked by non-dominant focal epilepsy: a case report.

ABSTRACT: Language lateralization in patients with focal epilepsy frequently diverges from the left-lateralized pattern that prevails in healthy right-handed people, but the mechanistic explanations are still a matter of debate. Here, we debate the complex interaction between focal epilepsy, language lateralization, and functional neuroimaging techniques by introducing the case of a right-handed patient with unaware focal seizures preceded by aphasia, in whom video-EEG and PET examination suggested the presence of focal cortical dysplasia in the right superior temporal gyrus, despite a normal structural MRI. The functional MRI for language was inconclusive, and the neuropsychological evaluation showed mild deficits in language functions. A bilateral stereo-EEG was proposed confirming the right super

SUBMITTER: Abarrategui B 

PROVIDER: S-EPMC10600519 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature