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Urea Hydrogen Peroxide and Ethyl Lactate, an Eco-Friendly Combo System in the Direct C(sp²)-H Bond Selenylation of Imidazo[2,1-b]thiazole and Related Structures.

ABSTRACT: Herein, we describe a urea hydrogen peroxide-mediated sustainable protocol for the synthesis of selenylated imidazo[2,1-b]thiazole by using half molar equivalent diorganyl diselenides in ethyl lactate as a greener solvent. The reaction features high yields, easy performance on gram scale, metal-free conditions, as well as applicability to imidazopyridine and imidazopyrimidine.

SUBMITTER: Moraes CAO

PROVIDER: S-EPMC10600889 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature

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Urea Hydrogen Peroxide and Ethyl Lactate, an Eco-Friendly Combo System in the Direct C(sp²)-H Bond Selenylation of Imidazo[2,1-b]thiazole and Related Structures.

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Dataset Information

Urea Hydrogen Peroxide and Ethyl Lactate, an Eco-Friendly Combo System in the Direct C(sp2)-H Bond Selenylation of Imidazo[2,1-b]thiazole and Related Structures.

OmicsDI is part of the ELIXIR infrastructure

Tweets

Urea Hydrogen Peroxide and Ethyl Lactate, an Eco-Friendly Combo System in the Direct C(sp²)-H Bond Selenylation of Imidazo[2,1-b]thiazole and Related Structures.