Effect of anatomical variation on extracorporeal membrane oxygenation circulatory support: A computational study.

ABSTRACT:

Background

Extracorporeal membrane oxygenation (ECMO) via femoral cannulation is a vital intervention capable of rapidly restoring perfusion for patients in shock. Despite increasing use to provide circulatory support, its hemodynamic effects are poorly understood and the impact of patient-specific anatomical variation on perfusion is unknown. This study investigates the complex failing heart-mechanical circulatory support circulation and analyzes the effect of patient-specific vascular anatomical variations on hemodynamics and end-organ perfusion.

Methods

Patient-specific vascular geometries were constructed from segmenting clinical computerized tomography angiography images and quantitatively compared using tortuosity, curvature, torsion, and lumen diameter. Computational

SUBMITTER: Khodaee F 

PROVIDER: S-EPMC10600951 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature