Toward New Assessment of Knee Cartilage Degeneration.

ABSTRACT:

Objective

Assessment of human joint cartilage is a crucial tool to detect and diagnose pathological conditions. This exploratory study developed a workflow for 3D modeling of cartilage and bone based on multimodal imaging. New evaluation metrics were created and, a unique set of data was gathered from healthy controls and patients with clinically evaluated degeneration or trauma.

Design

We present a novel methodology to evaluate knee bone and cartilage based on features extracted from magnetic resonance imaging (MRI) and computed tomography (CT) data. We developed patient specific 3D models of the tibial, femoral, and patellar bones and cartilages. Forty-seven subjects with a history of degenerative disease, traumatic events, or no symptoms or trauma (control group) were rec

SUBMITTER: Aubonnet R 

PROVIDER: S-EPMC10601563 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature