Testosterone therapy and venous thromboembolism: A systematic review and meta-analysis.

ABSTRACT:

Background

Testosterone prescribing for men has dramatically increased, and there have been concerns about inappropriate use and adverse events. While regulatory bodies have warned about increased risk of venous thromboembolism (VTE), published clinical data supporting an increased risk for VTE are limited.

Objective

To conduct a systematic review of studies examining the association between testosterone therapy in men and VTE.

Methods

Comprehensive searches of multiple databases were performed from inception through October 3rd, 2018. Randomized control trials (RCTs) and observational studies examining the association between exogenous testosterone (any route) and VTE. Study selection and data extraction were performed by two independent investigators. Random-effect

SUBMITTER: Houghton DE 

PROVIDER: S-EPMC10601700 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature