First Female Patient with a Rare CIC-FOXO4-Translocated Sarcoma: A Case Report.

ABSTRACT: Small round cell sarcoma is a group of undifferentiated malignancies arising in the bone and soft tissue, notable for Ewing sarcoma. Recently, a new World Health Organization classification has been introduced, including an additional subset of these sarcomas, named CIC-rearranged sarcoma. Within this group, CIC-FOXO4 translocation is an exceedingly rare fusion that has been reported only 4 times in the literature. Herein, we report in-depth the pathological, clinical, and molecular features of a CIC-FOXO4 translocation-driven tumor in a 46-year-old woman.

SUBMITTER: Babkoff A 

PROVIDER: S-EPMC10601800 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature