Antimicrobial drug resistant features of Mycobacterium tuberculosis associated with treatment failure.

ABSTRACT: Tuberculosis stands as a prominent cause of mortality in developing countries. The treatment of tuberculosis involves a complex procedure requiring the administration of a panel of at least four antimicrobial drugs for the duration of six months. The occurrence of treatment failure after the completion of a standard treatment course presents a serious medical problem. The purpose of this study was to evaluate antimicrobial drug resistant features of Mycobacterium tuberculosis associated with treatment failure. Additionally, it aimed to evaluate the effectiveness of second line drugs such as amikacin, linezolid, moxifloxacin, and the efflux pump inhibitor verapamil against M. tuberculosis isolates associated with treatment failure. We monitored 1200 tuberculosis patients who visited TB cent

SUBMITTER: Mushtaq F 

PROVIDER: S-EPMC10602240 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature