Neoadjuvant stereotactic radiosurgery for brain metastases: a new paradigm.

ABSTRACT:

Objective

For patients with surgically accessible solitary metastases or oligometastatic disease, treatment often involves resection followed by postoperative stereotactic radiosurgery (SRS). This strategy has several potential drawbacks, including irregular target delineation for SRS and potential tumor "seeding" away from the resection cavity during surgery. A neoadjuvant (preoperative) approach to radiation therapy avoids these limitations and offers improved patient convenience. This study assessed the efficacy of neoadjuvant SRS as a new treatment paradigm for patients with brain metastases.

Methods

A retrospective review was performed at a single institution to identify patients who had undergone neoadjuvant SRS (specifically, Gamma Knife radiosurgery) followed by rese

SUBMITTER: Li YD 

PROVIDER: S-EPMC10602665 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature