Pattern and time point of relapse in locally advanced esophagogastric adenocarcinoma after multimodal treatment: implications for a useful structured follow-up.

ABSTRACT:

Purpose

Despite improvements in multimodal treatment of locally advanced esophagogastric adenocarcinoma, the majority of patients still relapses. The impact of structured follow-up for early detection of recurrence is unclear and controversially discussed.

Methods

Patients with locally advanced esophagogastric adenocarcinoma having received neoadjuvant/perioperative chemotherapy followed by tumor resection between 2009 and 2021, underwent a structured follow-up including three-monthly imaging during the first 2 years, followed by semiannual and annual examinations in year 3-4 and 5, respectively. Clinical outcome including pattern and time point of relapse was analyzed.

Results

Two hundred fifty-seven patients were included in this analysis. In 50.2% (n = 129) of pati

SUBMITTER: Stelmach R 

PROVIDER: S-EPMC10602954 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature