Baseline ¹⁸F-FDG PET/CT radiomics for prognosis prediction in diffuse large B cell lymphoma.

ABSTRACT:

Background

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma in adults. Standard treatment includes chemoimmunotherapy with R-CHOP or similar regimens. Despite treatment advancements, many patients with DLBCL experience refractory disease or relapse. While baseline ¹⁸F-fluorodeoxyglucose positron emission tomography (¹⁸F-FDG PET) parameters have shown promise in predicting survival, they may not fully capture lesion heterogeneity. This study aimed to assess the prognostic value of baseline ¹⁸F-FDG PET radiomics features in comparison with clinical factors and metabolic parameters for assessing 2-year progression-free survival (PFS) and 5-year overall survival (OS) in patients with DLBCL.

Results

A total

SUBMITTER: Jing F 

PROVIDER: S-EPMC10603012 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature