The modular biochemical reaction network structure of cellular translation.

ABSTRACT: Translation is an essential attribute of all living cells. At the heart of cellular operation, it is a chemical information decoding process that begins with an input string of nucleotides and ends with the synthesis of a specific output string of peptides. The translation process is interconnected with gene expression, physiological regulation, transcription, and responses to signaling molecules, among other cellular functions. Foundational efforts have uncovered a wealth of knowledge about the mechanistic functions of the components of translation and their many interactions between them, but the broader biochemical connections between translation, metabolism and polymer biosynthesis that enable translation to occur have not been comprehensively mapped. Here we present a multilayer graph

SUBMITTER: Cuevas-Zuviria B 

PROVIDER: S-EPMC10603163 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature