Prevalence and prognosis of bone metastases in common solid cancers at initial diagnosis: a population-based study.

ABSTRACT:

Objective

Bone is one of the most common target sites for advanced tumours. The objective was to survey the prevalence and prognosis of bone metastases in 12 common solid malignant tumours.

Design

A retrospective cohort study.

Methods

A total of 1 425 332 patients with a primary cancer between 2010 and 2015 were identified using the Surveillance, Epidemiology, and End Results database. We computed the prevalence and prognosis of bone metastases in each cancer and compared their survival in different stages. The Kaplan-Meier method and Cox logistic regression were used to analyse survival and quantify the effect of bone metastases.

Results

This study included 89 782 patients with bone metastases at diagnosis. Lung cancer had the highest prevalence (18.05%), foll

SUBMITTER: Zhang J 

PROVIDER: S-EPMC10603455 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature