Epidemiology and clinical severity of the serotypes of human parainfluenza virus in children with acute respiratory infection.

ABSTRACT:

Background

Acute respiratory infections (ARI) are a threat to human health and survival, resulting in many paediatric hospitalisations. However, the epidemiological and clinical severity characteristics of the human parainfluenza virus (PIV), one of the most prevalent respiratory viruses, are not well understood in children.

Methods

To identify the epidemiological features of PIV infection, in 2019, hospitalised children with ARI were screened using multiplex polymerase chain reaction (PCR) for PIV and 10 other common respiratory pathogens. Subtyping of randomly selected PIV-positive samples was performed using reverse transcription-PCR. Demographics, epidemiology, clinical manifestations, diagnosis, and outcomes were compared between PIV subtypes.

Results

The annual

SUBMITTER: Wang L 

PROVIDER: S-EPMC10604402 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature