Non-contrast low-dose CT can be used for volumetry of ADPKD.

ABSTRACT:

Background

Kidney volume provides important information for the diagnosis and prognosis of autosomal dominant polycystic kidney disease (ADPKD), as well as for the evaluation of the effects of drugs such as tolvaptan. Non-contrast computed tomography (CT) is commonly used for volumetry, and this study examined the correspondence and correlation of kidney volume measured by standard-dose or low-dose CT.

Methods

Axial standard-dose and low-dose CT images with 1-mm slices were obtained from 24 ADPKD patients. The kidney was segmented in the Synapse 3D software and the kidney volume was calculated using stereology. The kidney volume was compared between the two sets of images using R², Bland-Altman plots, coefficient of variation, and intra-class correlation coefficie

SUBMITTER: Yoo J 

PROVIDER: S-EPMC10604523 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature