Theta and Gamma Activity Differences in Obsessive-Compulsive Disorder and Panic Disorder: Insights from Resting-State EEG with eLORETA.

ABSTRACT: Background: Obsessive-compulsive disorder (OCD) and panic disorder (PD) are debilitating psychiatric conditions, yet their underlying neurobiological differences remain underexplored. This study aimed to directly compare resting-state EEGs in patients with OCD and PD, without a healthy control group, using the eLORETA method. Methods: We collected retrospective EEG data from 24 OCD patients and 22 PD patients who were hospitalized due to significant impairment in daily life functions. eLORETA was used to analyze the EEG data. Results: Heightened theta activity was observed in the anterior cingulate cortex (ACC) of OCD patients compared to PD patients (PD vs. OCD, t = -2.168, p < 0.05). Conversely, higher gamma activity was found in the medial frontal gyrus (MFG)

SUBMITTER: Lee I 

PROVIDER: S-EPMC10605761 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature