Oscillometry of the respiratory system in Parkinson's disease: physiological changes and diagnostic use.

ABSTRACT:

Background

Lung function analysis in Parkinson's disease (PD) is often difficult due to the demand for adequate forced expiratory maneuvers. Respiratory oscillometry exams require onlyquiet tidal breathing and provide a detailed analysis of respiratory mechanics. We hypothesized that oscillometry would simplify the diagnosis of respiratory abnormalitiesin PD and improve our knowledge about the pathophysiological changes in these patients.

Materials and methods

This observational study includes 20 controls and 47 individuals with PD divided into three groups (Hoehn and Yahr Scale 1-1.5; H&Y scale 2-3 and PD smokers).The diagnostic accuracy was evaluated by investigating the area under the receiver operating characteristic curve (AUC).

Results

Initial stages are related

SUBMITTER: Caldas BT 

PROVIDER: S-EPMC10605979 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature