Effect of presentation rate on auditory processing in Rett syndrome: event-related potential study.

ABSTRACT:

Background

Rett syndrome (RS) is a rare neurodevelopmental disorder characterized by mutations in the MECP2 gene. Patients with RS have severe motor abnormalities and are often unable to walk, use hands and speak. The preservation of perceptual and cognitive functions is hard to assess, while clinicians and care-givers point out that these patients need more time to process information than typically developing peers. Neurophysiological correlates of auditory processing have been also found to be distorted in RS, but sound presentation rates were relatively quick in these studies (stimulus onset asynchrony, SOA < 1000 ms). As auditory event-related potential (ERP) is typically increased with prolongation of SOA we aim to study if SOA prolongation might compensate for observed abnor

SUBMITTER: Kostanian D 

PROVIDER: S-EPMC10605980 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature