Impacts of Population Size and Domestication Process on Genetic Diversity and Genetic Load in Genus Ovis.

ABSTRACT: In theoretical biology, a prevailing hypothesis posits a profound interconnection between effective population size (N_e), genetic diversity, inbreeding, and genetic load. The domestication and improvement processes are believed to be pivotal in diminishing genetic diversity while elevating levels of inbreeding and increasing genetic load. In this study, we performed a whole genome analysis to quantity genetic diversity, inbreeding, and genetic load across seven wild Ovis species and five domesticated sheep breeds. Our research demonstrates that the genetic load and diversity of species in the genus Ovis have no discernible impact on recent N_e, and three species within the subgenus Pachyceros tend to carry a higher genetic load and lo

SUBMITTER: Wang D 

PROVIDER: S-EPMC10606048 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature