Image Quality and Quantitative PET Parameters of Low-Dose [¹⁸F]FDG PET in a Long Axial Field-of-View PET/CT Scanner.

ABSTRACT: PET/CT scanners with a long axial field-of-view (LAFOV) provide increased sensitivity, enabling the adjustment of imaging parameters by reducing the injected activity or shortening the acquisition time. This study aimed to evaluate the limitations of reduced [¹⁸F]FDG activity doses on image quality, lesion detectability, and the quantification of lesion uptake in the Biograph Vision Quadra, as well as to assess the benefits of the recently introduced ultra-high sensitivity mode in a clinical setting. A number of 26 patients who underwent [¹⁸F]FDG-PET/CT (3.0 MBq/kg, 5 min scan time) were included in this analysis. The PET raw data was rebinned for shorter frame durations to simulate 5 min scans with lower activities in the high sensitivity (HS) and ultra-high sensitiv

SUBMITTER: Calderon E 

PROVIDER: S-EPMC10606613 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature