Testosterone and the Amygdala's Functional Connectivity in Women and Men.

ABSTRACT: The amygdala contains androgen receptors and is involved in various affective and social functions. An interaction between testosterone and the amygdala's functioning is likely. We investigated the amygdala's resting-state functional connectivity (rsFC) network in association with testosterone in 94 healthy young adult women and men (final data available for analysis from 42 women and 39 men). Across the whole sample, testosterone was positively associated with the rsFC between the right amygdala and the right middle occipital gyrus, and it further predicted lower agreeableness scores. Significant sex differences appeared for testosterone and the functional connectivity between the right amygdala and the right superior frontal gyrus (SFG), showing higher testosterone levels with lower conn

SUBMITTER: Kogler L 

PROVIDER: S-EPMC10607739 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature