Extraction and Purification of Highly Active Astaxanthin from Corynebacterium glutamicum Fermentation Broth.

ABSTRACT: The marine carotenoid astaxanthin is one of the strongest natural antioxidants and therefore is used in a broad range of applications such as cosmetics or nutraceuticals. To meet the growing market demand, the natural carotenoid producer Corynebacterium glutamicum has been engineered to produce astaxanthin by heterologous expression of genes from the marine bacterium Fulvimarina pelagi. To exploit this promising source of fermentative and natural astaxanthin, an efficient extraction process using ethanol was established in this study. Appropriate parameters for ethanol extraction were identified by screening ethanol concentration (62.5-97.5% v/v), temperature (30-70 °C) and biomass-to-solvent ratio (3.8-19.0 mg_CDW/mL_solvent). The results de

SUBMITTER: Seeger J 

PROVIDER: S-EPMC10608131 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature