The Genetic Code Assembles via Division and Fusion, Basic Cellular Events.

ABSTRACT: Standard Genetic Code (SGC) evolution is quantitatively modeled in up to 2000 independent coding 'environments'. Environments host multiple codes that may fuse or divide, with division yielding identical descendants. Code division may be selected-sophisticated gene products could be required for an orderly separation that preserves the coding. Several unforeseen results emerge: more rapid evolution requires unselective code division rather than its selective form. Combining selective and unselective code division, with/without code fusion, with/without independent environmental coding tables, and with/without wobble defines 2⁵ = 32 possible pathways for SGC evolution. These 32 possible histories are compared, specifically, for evolutionary speed and code accuracy. Pathways diffe

SUBMITTER: Yarus M 

PROVIDER: S-EPMC10608286 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature