The Role of Vitamins in Oral Potentially Malignant Disorders and Oral Cancer: A Systematic Review.

ABSTRACT:

Background

Micronutrients are vital for general and oral health, and their potential anti-cancer properties are documented. We explore beneficial vitamins for oral potentially malignant disorders (OPMDs) and oral cancer (OC), assessing the therapeutic impacts of essential vitamin supplementation.

Methods

We systematically review evidence on vitamin supplementation's therapeutic effects for OPMDs and OC. Relevant studies were identified through comprehensive searches of MEDLINE, Evidence-Based Medicine, and Web of Science until 16 May 2023. All studies underwent risk of bias using criteria modified from the Office of Health Assessment and Translation (OHAT) tool.

Results

We analysed 80 papers. Vitamin K, studied in vitro, shows promising therapeutic potential. Vitamin

SUBMITTER: See JKL 

PROVIDER: S-EPMC10608573 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature