Volumetric Absorptive Microsampling in the Analysis of Endogenous Metabolites.

ABSTRACT: Volumetric absorptive microsampling (VAMS) has arisen as a relevant tool in biological analysis, offering simplified sampling procedures and enhanced stability. Most of the attention VAMS has received in the past decade has been from pharmaceutical research, with most of the published work employing VAMS targeting drugs or other exogenous compounds, such as toxins and pollutants. However, biomarker analysis by employing blood microsampling has high promise. Herein, a comprehensive review on the applicability of VAMS devices for the analysis of endogenous metabolites/biomarkers was performed. The study presents a full overview of the analysis process, incorporating all the steps in sample treatment and validation parameters. Overall, VAMS devices have proven to be reliable tools for the ana

SUBMITTER: de Sa E Silva DM 

PROVIDER: S-EPMC10609074 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature