Biological Variation in Biochemistry Analytes in Laboratory Guinea Pigs (Cavia porcellus).

ABSTRACT: Biological variation (BV) describes the physiological random fluctuation around a homeostatic set point, which is a characteristic of all blood measurands (analytes). That variation may impact the clinical relevance of the changes that are observed in the serial results for an individual. Biological variation is represented mathematically by the coefficient of variation (CV) and occurs within each individual (CV_I) and between individuals in a population (CV_G). Biological variation data can be used to assess whether population-based reference or subject-based reference intervals should be used for the interpretation of laboratory results through the calculation of the index of individuality (IoI). This study aimed to determine the biological variations, calculate the I

SUBMITTER: Rossi G 

PROVIDER: S-EPMC10610888 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature