Extracellular Vesicles as a Translational Approach for the Treatment of COVID-19 Disease: An Updated Overview.

ABSTRACT: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic in the years 2020-2022. With a high prevalence, an easy route of transmission, and a long incubation time, SARS-CoV-2 spread quickly and affected public health and socioeconomic conditions. Several points need to be elucidated about its mechanisms of infection, in particular, its capability to evade the immune system and escape from neutralizing antibodies. Extracellular vesicles (EVs) are phospholipid bilayer-delimited particles that are involved in cell-to-cell communication; they contain biological information such as miRNAs, proteins, nucleic acids, and viral components. Abundantly released from biological fluids, their dimensions are highly variable, which are used to divide them into exosomes (40 to

SUBMITTER: Serretiello E 

PROVIDER: S-EPMC10611252 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature