Explore the changes of intestinal flora in patients with coronavirus disease 2019 based on bioinformatics.

ABSTRACT:

Background

Studies have revealed that there were significant changes in intestinal flora composition in patients with coronavirus disease 2019 (COVID-19) compared to non-COVID-19 patients, regardless of whether they were treated with medication. Therefore, a comprehensive study of the intestinal flora of COVID-19 patients is needed to further understand the mechanisms of COVID-19 development.

Methods

In total, 20 healthy samples and 20 COVID-19 samples were collected in this study. Firstly, alpha diversity and beta diversity were analyzed to assess whether there were difference in species richness and diversity as well as species composition between COVID-19 and control groups. The observed features index, Evenness index, PD index, and Shannon index were utilized to measure

SUBMITTER: Huang G 

PROVIDER: S-EPMC10611479 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature