All-cause and cause-specific mortality among people with bipolar disorder: a large-scale systematic review and meta-analysis.

ABSTRACT:

Objective

Bipolar disorder (BD) is associated with premature mortality. All-cause and specific mortality risks in this population remain unclear, and more studies are still needed to further understand this issue and guide individual and public strategies to prevent mortality in bipolar disorder Thus, a systematic review and meta-analysis of studies assessing mortality risk in people with BD versus the general population was conducted. The primary outcome was all-cause mortality, whilst secondary outcomes were mortality due to suicide, natural, unnatural, and specific-causes mortality.

Results

Fifty-seven studies were included (BD; n = 678,353). All-cause mortality was increased in people with BD (RR = 2.02, 95% CI: 1.89-2.16, k = 39). Specific-cause mortality was highest fo

SUBMITTER: Biazus TB 

PROVIDER: S-EPMC10611575 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature