Impact of cardiac history and myocardial scar on increase of myocardial perfusion after revascularization.

ABSTRACT:

Purpose

We sought to assess the impact of coronary revascularization on myocardial perfusion and fractional flow reserve (FFR) in patients without a cardiac history, with prior myocardial infarction (MI) or non-MI percutaneous coronary intervention (PCI). Furthermore, we studied the impact of scar tissue.

Methods

Symptomatic patients underwent [¹⁵O]H₂O positron emission tomography (PET) and FFR before and after revascularization. Patients with prior CAD, defined as prior MI or PCI, underwent scar quantification by magnetic resonance imaging late gadolinium enhancement.

Results

Among 137 patients (87% male, age 62.2 ± 9.5 years) 84 (61%) had a prior MI or PCI. The increase in FFR and hyperemic myocardial blood flow (hMBF) was less in patients with

SUBMITTER: Jukema RA 

PROVIDER: S-EPMC10611874 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature